Tuesday, September 30, 2014

Elkhart $SUBT_ON$Raza performs reflux disease study$SUBT_OFF$

Posted on June 4, 2013 at 1:00 a.m. | Updated on June 4, 2013 at 1:12 p.m.

ELKHART — Patients of Dr. Mamoon Raza, gastroenterologist at the Elkhart Clinic, participated in a prospective, randomized, controlled trial comparing the Transoral Incisionless Fundoplication procedure to daily doses of proton pump inhibitor medications to combat gastroesophageal reflux disease.

Raza was an investigator in the trial and presented the first six months of data during the American Gastroenterological Association’s Late-breaking abstract session at the 2013 DDW annual meeting in Orlando, Fla. Patients who underwent TIF procedures experienced significantly better outcomes in reduction of troublesome GERD symptoms after six months than patients who continued to take maximum daily doses of proton pump inhibitor medications.

“This randomized controlled study establishes for the first time that, for some patients, the TIF procedure is better than maximal dose PPI therapy in controlling a whole range of GERD symptoms,” Raza said. “Going forward, TIF should be offered as an alternative to the right patients who are not completely responsive to PPIs, or who are seeking to avoid the long-term side effects of medications.”

Daily troublesome heartburn was eliminated in 90 percent of patients in the TIF group versus only 13 percent in the PPI group, and 90 percent of patients in the TIF group completely ceased PPI use.

Standard recommendations for symptomatic GERD patients include lifestyle changes such as diet or scheduled eating times, and escalating doses of prescription medications for prolonged periods.